Serveur d'exploration sur la rapamycine et les champignons

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

The putative histone-like transcription factor FgHltf1 is required for vegetative growth, sexual reproduction, and virulence in Fusarium graminearum.

Identifieur interne : 000192 ( Main/Exploration ); précédent : 000191; suivant : 000193

The putative histone-like transcription factor FgHltf1 is required for vegetative growth, sexual reproduction, and virulence in Fusarium graminearum.

Auteurs : Wuyun Lv [République populaire de Chine] ; Jinjin Wu [République populaire de Chine] ; Zhe Xu [République populaire de Chine] ; Han Dai [République populaire de Chine] ; Zhonghua Ma [République populaire de Chine] ; Zhengyi Wang [République populaire de Chine]

Source :

RBID : pubmed:30852625

Descripteurs français

English descriptors

Abstract

The target of rapamycin (TOR) signaling pathway plays critical roles in regulating vegetative development and virulence in Fusarium graminearum. Previously, we have demonstrated that the putative type 2A phosphatase FgPpg1, a downstream component of the pathway, is important for hyphal growth, sporulation, DON biosynthesis and virulence. Here, we report the identification of FgHLTF1 putatively encoding a histone-like transcription factor by the transcriptome analysis of an ΔFgppg1 mutant. The FgHLTF1 expression was significantly down-regulated by the deletion of FgPPG1 or treatment with rapamycin. Analysis of an F. graminearum strain expressing green fluorescent protein (GFP) revealed that FgHltf1-GFP fusion protein mainly localized to the nucleus. Targeted gene deletion mutants of FgHLTF1 exhibited a significant reduction in vegetative growth, sexual reproduction and virulence. Moreover, the growth of the ΔFghltf1 mutants was restricted by hyperosmotic stresses. Unlike the wild-type strain, the mutants showed anomalous subcellular translocation of FgHog1-GFP under hyperosmotic conditions, suggesting that FgHLTF1 is associated with the high osmolarity glycerol response pathway. Taken together, we conclude that FgHLTF1 is transcriptionally regulated by the TOR signaling pathway and plays important roles in regulating vegetative growth, sexual reproduction, virulence and hyperosmotic stresses in F. graminearum.

DOI: 10.1007/s00294-019-00953-3
PubMed: 30852625


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">The putative histone-like transcription factor FgHltf1 is required for vegetative growth, sexual reproduction, and virulence in Fusarium graminearum.</title>
<author>
<name sortKey="Lv, Wuyun" sort="Lv, Wuyun" uniqKey="Lv W" first="Wuyun" last="Lv">Wuyun Lv</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wu, Jinjin" sort="Wu, Jinjin" uniqKey="Wu J" first="Jinjin" last="Wu">Jinjin Wu</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Xu, Zhe" sort="Xu, Zhe" uniqKey="Xu Z" first="Zhe" last="Xu">Zhe Xu</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Dai, Han" sort="Dai, Han" uniqKey="Dai H" first="Han" last="Dai">Han Dai</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ma, Zhonghua" sort="Ma, Zhonghua" uniqKey="Ma Z" first="Zhonghua" last="Ma">Zhonghua Ma</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wang, Zhengyi" sort="Wang, Zhengyi" uniqKey="Wang Z" first="Zhengyi" last="Wang">Zhengyi Wang</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China. zhywang@zju.edu.cn.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PubMed</idno>
<date when="2019">2019</date>
<idno type="RBID">pubmed:30852625</idno>
<idno type="pmid">30852625</idno>
<idno type="doi">10.1007/s00294-019-00953-3</idno>
<idno type="wicri:Area/Main/Corpus">000322</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000322</idno>
<idno type="wicri:Area/Main/Curation">000322</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000322</idno>
<idno type="wicri:Area/Main/Exploration">000322</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">The putative histone-like transcription factor FgHltf1 is required for vegetative growth, sexual reproduction, and virulence in Fusarium graminearum.</title>
<author>
<name sortKey="Lv, Wuyun" sort="Lv, Wuyun" uniqKey="Lv W" first="Wuyun" last="Lv">Wuyun Lv</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wu, Jinjin" sort="Wu, Jinjin" uniqKey="Wu J" first="Jinjin" last="Wu">Jinjin Wu</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Xu, Zhe" sort="Xu, Zhe" uniqKey="Xu Z" first="Zhe" last="Xu">Zhe Xu</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Dai, Han" sort="Dai, Han" uniqKey="Dai H" first="Han" last="Dai">Han Dai</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Ma, Zhonghua" sort="Ma, Zhonghua" uniqKey="Ma Z" first="Zhonghua" last="Ma">Zhonghua Ma</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Wang, Zhengyi" sort="Wang, Zhengyi" uniqKey="Wang Z" first="Zhengyi" last="Wang">Zhengyi Wang</name>
<affiliation wicri:level="4">
<nlm:affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China. zhywang@zju.edu.cn.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName>
<settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Current genetics</title>
<idno type="eISSN">1432-0983</idno>
<imprint>
<date when="2019" type="published">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Cell Wall (genetics)</term>
<term>Fusarium (genetics)</term>
<term>Fusarium (pathogenicity)</term>
<term>Gene Expression Regulation, Fungal (MeSH)</term>
<term>Histones (genetics)</term>
<term>Hyphae (genetics)</term>
<term>Hyphae (growth & development)</term>
<term>Mutant Proteins (genetics)</term>
<term>Osmotic Pressure (physiology)</term>
<term>Reproduction (genetics)</term>
<term>Signal Transduction (genetics)</term>
<term>Spores, Fungal (genetics)</term>
<term>Spores, Fungal (growth & development)</term>
<term>TOR Serine-Threonine Kinases (genetics)</term>
<term>Transcription Factors (genetics)</term>
<term>Transcriptome (genetics)</term>
<term>Virulence (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Facteurs de transcription (génétique)</term>
<term>Fusarium (génétique)</term>
<term>Fusarium (pathogénicité)</term>
<term>Histone (génétique)</term>
<term>Hyphae (croissance et développement)</term>
<term>Hyphae (génétique)</term>
<term>Paroi cellulaire (génétique)</term>
<term>Pression osmotique (physiologie)</term>
<term>Protéines mutantes (génétique)</term>
<term>Reproduction (génétique)</term>
<term>Régulation de l'expression des gènes fongiques (MeSH)</term>
<term>Spores fongiques (croissance et développement)</term>
<term>Spores fongiques (génétique)</term>
<term>Sérine-thréonine kinases TOR (génétique)</term>
<term>Transcriptome (génétique)</term>
<term>Transduction du signal (génétique)</term>
<term>Virulence (génétique)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en">
<term>Histones</term>
<term>Mutant Proteins</term>
<term>TOR Serine-Threonine Kinases</term>
<term>Transcription Factors</term>
</keywords>
<keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr">
<term>Hyphae</term>
<term>Spores fongiques</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>Cell Wall</term>
<term>Fusarium</term>
<term>Hyphae</term>
<term>Reproduction</term>
<term>Signal Transduction</term>
<term>Spores, Fungal</term>
<term>Transcriptome</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" qualifier="growth & development" xml:lang="en">
<term>Hyphae</term>
<term>Spores, Fungal</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr">
<term>Facteurs de transcription</term>
<term>Fusarium</term>
<term>Histone</term>
<term>Hyphae</term>
<term>Paroi cellulaire</term>
<term>Protéines mutantes</term>
<term>Reproduction</term>
<term>Spores fongiques</term>
<term>Sérine-thréonine kinases TOR</term>
<term>Transcriptome</term>
<term>Transduction du signal</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en">
<term>Fusarium</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr">
<term>Fusarium</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr">
<term>Pression osmotique</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Osmotic Pressure</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Gene Expression Regulation, Fungal</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Régulation de l'expression des gènes fongiques</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">The target of rapamycin (TOR) signaling pathway plays critical roles in regulating vegetative development and virulence in Fusarium graminearum. Previously, we have demonstrated that the putative type 2A phosphatase FgPpg1, a downstream component of the pathway, is important for hyphal growth, sporulation, DON biosynthesis and virulence. Here, we report the identification of FgHLTF1 putatively encoding a histone-like transcription factor by the transcriptome analysis of an ΔFgppg1 mutant. The FgHLTF1 expression was significantly down-regulated by the deletion of FgPPG1 or treatment with rapamycin. Analysis of an F. graminearum strain expressing green fluorescent protein (GFP) revealed that FgHltf1-GFP fusion protein mainly localized to the nucleus. Targeted gene deletion mutants of FgHLTF1 exhibited a significant reduction in vegetative growth, sexual reproduction and virulence. Moreover, the growth of the ΔFghltf1 mutants was restricted by hyperosmotic stresses. Unlike the wild-type strain, the mutants showed anomalous subcellular translocation of FgHog1-GFP under hyperosmotic conditions, suggesting that FgHLTF1 is associated with the high osmolarity glycerol response pathway. Taken together, we conclude that FgHLTF1 is transcriptionally regulated by the TOR signaling pathway and plays important roles in regulating vegetative growth, sexual reproduction, virulence and hyperosmotic stresses in F. graminearum.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">30852625</PMID>
<DateCompleted>
<Year>2019</Year>
<Month>12</Month>
<Day>03</Day>
</DateCompleted>
<DateRevised>
<Year>2020</Year>
<Month>02</Month>
<Day>25</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1432-0983</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>65</Volume>
<Issue>4</Issue>
<PubDate>
<Year>2019</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>Current genetics</Title>
<ISOAbbreviation>Curr Genet</ISOAbbreviation>
</Journal>
<ArticleTitle>The putative histone-like transcription factor FgHltf1 is required for vegetative growth, sexual reproduction, and virulence in Fusarium graminearum.</ArticleTitle>
<Pagination>
<MedlinePgn>981-994</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s00294-019-00953-3</ELocationID>
<Abstract>
<AbstractText>The target of rapamycin (TOR) signaling pathway plays critical roles in regulating vegetative development and virulence in Fusarium graminearum. Previously, we have demonstrated that the putative type 2A phosphatase FgPpg1, a downstream component of the pathway, is important for hyphal growth, sporulation, DON biosynthesis and virulence. Here, we report the identification of FgHLTF1 putatively encoding a histone-like transcription factor by the transcriptome analysis of an ΔFgppg1 mutant. The FgHLTF1 expression was significantly down-regulated by the deletion of FgPPG1 or treatment with rapamycin. Analysis of an F. graminearum strain expressing green fluorescent protein (GFP) revealed that FgHltf1-GFP fusion protein mainly localized to the nucleus. Targeted gene deletion mutants of FgHLTF1 exhibited a significant reduction in vegetative growth, sexual reproduction and virulence. Moreover, the growth of the ΔFghltf1 mutants was restricted by hyperosmotic stresses. Unlike the wild-type strain, the mutants showed anomalous subcellular translocation of FgHog1-GFP under hyperosmotic conditions, suggesting that FgHLTF1 is associated with the high osmolarity glycerol response pathway. Taken together, we conclude that FgHLTF1 is transcriptionally regulated by the TOR signaling pathway and plays important roles in regulating vegetative growth, sexual reproduction, virulence and hyperosmotic stresses in F. graminearum.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Lv</LastName>
<ForeName>Wuyun</ForeName>
<Initials>W</Initials>
<AffiliationInfo>
<Affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wu</LastName>
<ForeName>Jinjin</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Xu</LastName>
<ForeName>Zhe</ForeName>
<Initials>Z</Initials>
<AffiliationInfo>
<Affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Dai</LastName>
<ForeName>Han</ForeName>
<Initials>H</Initials>
<AffiliationInfo>
<Affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Ma</LastName>
<ForeName>Zhonghua</ForeName>
<Initials>Z</Initials>
<AffiliationInfo>
<Affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wang</LastName>
<ForeName>Zhengyi</ForeName>
<Initials>Z</Initials>
<AffiliationInfo>
<Affiliation>State Key Laboratory of Rice Biology and Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Biotechnology, Zhejiang University, Hangzhou, 310029, China. zhywang@zju.edu.cn.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y">
<Grant>
<GrantID>2013CB127802</GrantID>
<Agency>National Key Basic Research and Development Program</Agency>
<Country></Country>
</Grant>
</GrantList>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic">
<Year>2019</Year>
<Month>03</Month>
<Day>09</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo>
<Country>United States</Country>
<MedlineTA>Curr Genet</MedlineTA>
<NlmUniqueID>8004904</NlmUniqueID>
<ISSNLinking>0172-8083</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D006657">Histones</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D050505">Mutant Proteins</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014157">Transcription Factors</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>EC 2.7.1.1</RegistryNumber>
<NameOfSubstance UI="D058570">TOR Serine-Threonine Kinases</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D002473" MajorTopicYN="N">Cell Wall</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005670" MajorTopicYN="N">Fusarium</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015966" MajorTopicYN="N">Gene Expression Regulation, Fungal</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006657" MajorTopicYN="N">Histones</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D025301" MajorTopicYN="N">Hyphae</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D050505" MajorTopicYN="N">Mutant Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D009997" MajorTopicYN="N">Osmotic Pressure</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012098" MajorTopicYN="N">Reproduction</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015398" MajorTopicYN="N">Signal Transduction</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D013172" MajorTopicYN="N">Spores, Fungal</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D058570" MajorTopicYN="N">TOR Serine-Threonine Kinases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D014157" MajorTopicYN="N">Transcription Factors</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D059467" MajorTopicYN="N">Transcriptome</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D014774" MajorTopicYN="N">Virulence</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">FgHltf1</Keyword>
<Keyword MajorTopicYN="N">Fusarium graminearum</Keyword>
<Keyword MajorTopicYN="N">HOG</Keyword>
<Keyword MajorTopicYN="N">Pathogenicity</Keyword>
<Keyword MajorTopicYN="N">TOR</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData>
<History>
<PubMedPubDate PubStatus="received">
<Year>2018</Year>
<Month>09</Month>
<Day>14</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted">
<Year>2019</Year>
<Month>02</Month>
<Day>20</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised">
<Year>2019</Year>
<Month>02</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed">
<Year>2019</Year>
<Month>3</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2019</Year>
<Month>12</Month>
<Day>4</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez">
<Year>2019</Year>
<Month>3</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList>
<ArticleId IdType="pubmed">30852625</ArticleId>
<ArticleId IdType="doi">10.1007/s00294-019-00953-3</ArticleId>
<ArticleId IdType="pii">10.1007/s00294-019-00953-3</ArticleId>
</ArticleIdList>
<ReferenceList>
<Reference>
<Citation>Gene. 1999 Oct 18;239(1):15-27</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">10571030</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Genes Dev. 2000 Oct 15;14(20):2551-69</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">11040209</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Gene. 2001 Feb 21;264(2):173-85</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">11250072</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biol Chem. 2002 Feb 22;277(8):5841-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">11689552</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Methods. 2001 Dec;25(4):402-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">11846609</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biol Chem. 2003 Jan 10;278(2):1336-45</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">12401788</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Gen Genet. 1992 Oct;235(1):81-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">1435733</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Nucleic Acids Res. 1992 Mar 11;20(5):1087-91</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">1549471</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biochem. 2004 Sep;136(3):267-72</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">15598881</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant J. 2005 May;42(3):364-75</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">15842622</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Microbiol. 2005 Nov;58(4):1102-13</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">16262793</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Eukaryot Cell. 2005 Nov;4(11):1829-39</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">16278450</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Microbiol. 2006 Aug;61(4):1069-80</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">16879655</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Fungal Genet Biol. 2007 Nov;44(11):1191-204</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">17451976</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Cell. 2007 Jun 8;26(5):663-74</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">17560372</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>EMBO J. 2007 Jul 11;26(13):3098-108</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">17568771</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Int J Food Microbiol. 2007 Oct 20;119(1-2):103-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">17716761</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Biochim Biophys Acta. 2007 Oct;1770(10):1475-82</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">17728068</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Curr Opin Microbiol. 2008 Apr;11(2):153-60</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">18396450</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>FEMS Microbiol Lett. 2008 Sep;286(2):145-51</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">18789126</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1968-72</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">2000400</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Plant Pathol. 2004 Nov 1;5(6):515-25</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">20565626</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Plant Microbe Interact. 2011 Jan;24(1):54-67</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">20879840</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Fungal Genet Biol. 2011 Mar;48(3):217-24</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">21094265</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>PLoS Pathog. 2011 Oct;7(10):e1002310</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22028654</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>PLoS Pathog. 2012;8(5):e1002724</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22693448</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>FEMS Microbiol Lett. 2012 Sep;334(1):66-73</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22702217</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>PLoS One. 2012;7(11):e49495</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">23166686</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Cancer. 2012 Dec 12;11:90</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">23234329</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Mol Biol. 1990 Apr 20;212(4):563-78</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">2329577</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Microbiology. 2013 Jun;159(Pt 6):1077-85</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">23619001</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Plant Cell. 2014 Mar;26(3):1009-17</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">24610724</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>New Phytol. 2014 Jul;203(1):219-32</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">24684168</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Phytopathology. 2014 Nov;104(11):1201-7</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">24779355</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Plant Pathol. 2015 Jan;16(1):1-13</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">24832137</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Fungal Genet Biol. 2014 Aug;69:52-64</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">24875423</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Environ Microbiol. 2015 Aug;17(8):2661-76</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">24903410</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Environ Microbiol. 2016 Nov;18(11):3689-3701</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">26940955</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Environ Microbiol. 2016 Nov;18(11):3742-3757</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">26971885</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Front Cell Dev Biol. 2017 Jun 07;5:61</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">28638821</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Environ Microbiol. 2017 Oct;19(10):4065-4079</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">28654215</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Plant Microbe Interact. 2017 Nov;30(11):886-895</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">28800710</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Curr Genet. 2018 Feb;64(1):285-301</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">28918485</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Plant Pathol. 2018 Jul;19(7):1595-1611</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">29077257</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Curr Genet. 2018 Oct;64(5):1057-1069</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">29502265</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Curr Genet. 2019 Feb;65(1):153-166</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">29947970</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Nucleic Acids Res. 1995 Jul 25;23(14):2685-91</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">7651829</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Biol Chem. 1995 Sep 8;270(36):20978-86</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">7673122</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1624-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">7878029</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Proc Natl Acad Sci U S A. 1994 Jan 18;91(2):554-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">8290561</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Plant Microbe Interact. 1995 Jul-Aug;8(4):593-601</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">8589414</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Bacteriol. 1996 Jul;178(13):3908-16</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">8682797</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Eur J Biochem. 1996 Jun 15;238(3):675-82</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">8706667</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Genes Dev. 1996 Aug 1;10(15):1904-16</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">8756348</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>J Lipid Res. 1998 Apr;39(4):767-76</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">9555942</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Trends Biochem Sci. 1998 May;23(5):174-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">9612081</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Annu Rev Biochem. 1998;67:545-79</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">9759497</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Mol Cell Biol. 1999 Jan;19(1):99-106</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">9858535</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations>
<list>
<country>
<li>République populaire de Chine</li>
</country>
<region>
<li>Zhejiang</li>
</region>
<settlement>
<li>Hangzhou</li>
</settlement>
<orgName>
<li>Université de Zhejiang</li>
</orgName>
</list>
<tree>
<country name="République populaire de Chine">
<region name="Zhejiang">
<name sortKey="Lv, Wuyun" sort="Lv, Wuyun" uniqKey="Lv W" first="Wuyun" last="Lv">Wuyun Lv</name>
</region>
<name sortKey="Dai, Han" sort="Dai, Han" uniqKey="Dai H" first="Han" last="Dai">Han Dai</name>
<name sortKey="Ma, Zhonghua" sort="Ma, Zhonghua" uniqKey="Ma Z" first="Zhonghua" last="Ma">Zhonghua Ma</name>
<name sortKey="Wang, Zhengyi" sort="Wang, Zhengyi" uniqKey="Wang Z" first="Zhengyi" last="Wang">Zhengyi Wang</name>
<name sortKey="Wu, Jinjin" sort="Wu, Jinjin" uniqKey="Wu J" first="Jinjin" last="Wu">Jinjin Wu</name>
<name sortKey="Xu, Zhe" sort="Xu, Zhe" uniqKey="Xu Z" first="Zhe" last="Xu">Zhe Xu</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/RapamycinFungusV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000192 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000192 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    RapamycinFungusV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:30852625
   |texte=   The putative histone-like transcription factor FgHltf1 is required for vegetative growth, sexual reproduction, and virulence in Fusarium graminearum.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:30852625" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a RapamycinFungusV1 

Wicri

This area was generated with Dilib version V0.6.38.
Data generation: Thu Nov 19 21:55:41 2020. Site generation: Thu Nov 19 22:00:39 2020